{
  "schema_version": "1.0.0",
  "title": "Canadian Long COVID trials and studies",
  "checked": "2026-10-16",
  "timezone": "America/Toronto",
  "scope": "Canadian sites or Canadian-led Long COVID research; current, planned and unresolved listings. This is not an exhaustive census.",
  "methodology": {
    "registry_searches": [
      "https://clinicaltrials.gov/api/v2/studies?query.cond=%22long%20COVID%22%20OR%20%22post%20COVID%22%20OR%20%22post-acute%20COVID%22%20OR%20%22post%20COVID-19%20condition%22&query.locn=Canada&pageSize=100&countTotal=true&format=json",
      "https://clinicaltrials.gov/api/v2/studies?query.term=(PASC%20OR%20%22post-acute%20sequelae%22%20OR%20%22post%20COVID%22%20OR%20%22long%20COVID%22%20OR%20%22long-COVID%22%20OR%20%22post-COVID%22%20OR%20%22post%20coronavirus%22)&query.locn=Canada&pageSize=100&countTotal=true&format=json&fields=NCTId,BriefTitle,OverallStatus,LastUpdatePostDate,BriefSummary,LocationCountry"
    ],
    "broad_search_records": 61,
    "narrow_search_records": 46,
    "sources": [
      "ClinicalTrials.gov",
      "Long COVID Web",
      "RECLAIM",
      "Institutional and research-team pages"
    ],
    "rules": [
      "Exclude completed, terminated and withdrawn studies from participation listings.",
      "Separate acute-COVID prevention studies and unrelated keyword matches.",
      "An overall UNKNOWN status overrides an old recruiting site label.",
      "Recruiting registry records last updated more than 12 months ago go under Needs confirmation unless an official study-team page explicitly lists current enrolment; retain any site discrepancies and identify that source.",
      "Undated or old posters without current study-team confirmation go under Needs confirmation.",
      "Upcoming means explicitly not yet recruiting; dates are estimates.",
      "Province may identify the study team or listed site; it does not establish geographic eligibility.",
      "Remote does not establish accessibility or nationwide eligibility.",
      "Counts describe listings, not necessarily distinct studies; possible linked recruitment posters are flagged until the team confirms their relationship."
    ],
    "coverage_audit": {
      "date": "2026-10-15",
      "broad_records": 61,
      "narrow_records": 46,
      "narrow_subset_of_broad": true,
      "scope": "ClinicalTrials.gov Canadian keyword searches plus targeted institutional and research-team pages; not an exhaustive census.",
      "result": "No missing eligible recruiting registry trial identified in these searches. Added one official online observational project. Reviewed registry status/update fields for existing matches without finding changes; individual full-record check dates are retained."
    }
  },
  "excluded_examples": [
    {
      "id": "NCT05430152",
      "reason": "Completed BC LDN trial"
    },
    {
      "id": "NCT05513560",
      "reason": "Completed original RECLAIM drug arms; newer arms have their own records"
    },
    {
      "id": "NCT06792214",
      "reason": "Acute-COVID prevention trial, not treatment of established Long COVID"
    },
    {
      "id": "NCT05938101",
      "reason": "Unrelated clinic-staff harassment study"
    },
    {
      "id": "NCT06695910",
      "reason": "General brain fog population, not specifically Long COVID"
    },
    {
      "id": "project-pots",
      "reason": "Poster recruitment deadline 30 May 2025 has passed; network listing still says recruiting"
    }
  ],
  "studies": [
    {
      "id": "NCT07627815",
      "title": "PNMR metabolic regulator",
      "summary": "Six-week randomized study comparing PNMR plus usual care with usual care alone. Clinic assessments and symptom diaries are part of participation.",
      "format": "In person",
      "type": "Clinical trial",
      "status": "RECRUITING",
      "status_group": "recruiting",
      "source_updated": "2026-06-04",
      "checked": "2026-10-13",
      "start": {
        "date": "2026-05-20",
        "type": "ACTUAL"
      },
      "age_min": "19 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "Cardio Health",
          "city": "Brampton",
          "province": "Ontario",
          "status": "RECRUITING"
        },
        {
          "facility": "Cardio Health",
          "city": "London",
          "province": "Ontario",
          "status": "RECRUITING"
        },
        {
          "facility": "Cardio Health",
          "city": "Mississauga",
          "province": "Ontario",
          "status": "RECRUITING"
        },
        {
          "facility": "Cardio Health",
          "city": "North York",
          "province": "Ontario",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Ontario"
      ],
      "contact": [
        {
          "name": "Samuel H. O. Bock / CSO, BA Environmental Science",
          "email": "sbock@paragonsciences.com",
          "phone": "514 998-3935"
        },
        {
          "name": "John S Sampalis, PHD Epidemiology",
          "email": "jsampalis@jssresearch.com",
          "phone": "514 934-6116"
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT07627815"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements."
    },
    {
      "id": "NCT06452095",
      "title": "RECLAIM — hyperbaric oxygen",
      "summary": "Tests hyperbaric oxygen for Long COVID cognitive symptoms. Ask the team about chamber visits, travel and the assessment schedule.",
      "format": "In person",
      "type": "Clinical trial",
      "status": "RECRUITING",
      "status_group": "recruiting",
      "source_updated": "2026-02-23",
      "checked": "2026-10-13",
      "start": {
        "date": "2026-01-01",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "University Health Network",
          "city": "Toronto",
          "province": "Ontario",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Ontario"
      ],
      "contact": [
        {
          "name": "RECLAIM CONTACT RECLAIM contact line",
          "email": "reclaim@uhn.ca",
          "phone": "1-866-673-2524"
        },
        {
          "name": "Andrew Janes, MSc",
          "email": "andrew.janes@uhn.ca",
          "phone": null
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT06452095"
        },
        {
          "label": "RECLAIM current sites and contacts",
          "url": "https://www.reclaimtrial.ca/contact-us"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements."
    },
    {
      "id": "NCT05040893",
      "title": "Tailored physiotherapy pilot",
      "summary": "Studies a tailored physiotherapy programme for persistent symptoms after COVID-19. The old registry entry does not establish current availability.",
      "format": "Confirm with team",
      "type": "Clinical trial",
      "status": "UNKNOWN",
      "status_group": "verify",
      "source_updated": "2023-08-29",
      "checked": "2026-10-13",
      "start": {
        "date": "2022-03-04",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "Peter Lougheed Centre (PLC), University of Calgary",
          "city": "Calgary",
          "province": "Alberta",
          "status": "Not specified"
        },
        {
          "facility": "Rockyview General Hospital, University of Calgary",
          "city": "Calgary",
          "province": "Alberta",
          "status": "Not specified"
        }
      ],
      "provinces": [
        "Alberta"
      ],
      "contact": [],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT05040893"
        },
        {
          "label": "Published pilot results (2025)",
          "url": "https://pubmed.ncbi.nlm.nih.gov/41132192/"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements.",
      "verification_note": "The registry remains unknown (last updated 29 August 2023); its last known status was active, not recruiting. Results from this registered pilot have since been published. No current invitation to enrol was found.",
      "verification_checked": "2026-10-13",
      "verification_method": "Public sources only; no study-team contact",
      "registry_last_known_status": "ACTIVE_NOT_RECRUITING"
    },
    {
      "id": "NCT06082518",
      "title": "Hyperbaric oxygen for post-COVID symptoms",
      "summary": "Studies hyperbaric oxygen treatment for post-COVID symptoms. Follow-up is ongoing; the registry says new participants are not being accepted.",
      "format": "In person",
      "type": "Clinical trial",
      "status": "ACTIVE_NOT_RECRUITING",
      "status_group": "ongoing",
      "source_updated": "2026-09-02",
      "checked": "2026-10-13",
      "start": {
        "date": "2024-01-02",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "Sunnybrook Health Sciences Centre",
          "city": "Toronto",
          "province": "Ontario",
          "status": "Not specified"
        }
      ],
      "provinces": [
        "Ontario"
      ],
      "contact": [],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT06082518"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements."
    },
    {
      "id": "NCT06933173",
      "title": "DNRS mind-body programme",
      "summary": "Randomized study of the Dynamic Neural Retraining System in ME/CFS, including participants with Long COVID. The proposed mechanism and benefit remain research questions.",
      "format": "Confirm with team",
      "type": "Clinical trial",
      "status": "RECRUITING",
      "status_group": "recruiting",
      "source_updated": "2026-09-09",
      "checked": "2026-10-13",
      "start": {
        "date": "2025-07-10",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "Peter Lougheed Hospital",
          "city": "Calgary",
          "province": "Alberta",
          "status": "RECRUITING"
        },
        {
          "facility": "University of Alberta Hospital/Kaye Edmonton Clinic",
          "city": "Edmonton",
          "province": "Alberta",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Alberta"
      ],
      "contact": [
        {
          "name": "MILES RCT team",
          "email": "rctmiles@ualberta.ca",
          "phone": "780-680-8907"
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT06933173"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements."
    },
    {
      "id": "NCT06721949",
      "title": "RECLAIM — taurine",
      "summary": "Randomized trial testing taurine against placebo for Long COVID fatigue and cognitive symptoms over 12 weeks.",
      "format": "In person",
      "type": "Clinical trial",
      "status": "RECRUITING",
      "status_group": "recruiting",
      "source_updated": "2026-09-18",
      "checked": "2026-10-14",
      "start": {
        "date": "2025-11-18",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "University of Alberta Hospital, Kaye Edmonton Clinic",
          "city": "Edmonton",
          "province": "Alberta",
          "status": "RECRUITING"
        },
        {
          "facility": "BC Women's Hospital",
          "city": "Vancouver",
          "province": "British Columbia",
          "status": "RECRUITING"
        },
        {
          "facility": "University Health Network",
          "city": "Toronto",
          "province": "Ontario",
          "status": "RECRUITING"
        },
        {
          "facility": "Institut de recherches cliniques de Montréal",
          "city": "Montreal",
          "province": "Quebec",
          "status": "RECRUITING"
        },
        {
          "facility": "Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre hospitalier universitaire de Sherbrooke",
          "city": "Sherbrooke",
          "province": "Quebec",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Alberta",
        "British Columbia",
        "Ontario",
        "Quebec"
      ],
      "contact": [
        {
          "name": "Lawrence Richer, MD, MSc",
          "email": "lricher@ualberta.ca",
          "phone": "780-492-0943"
        },
        {
          "name": "Ellen Morrison, PhD",
          "email": "taurineLC@ualberta.ca",
          "phone": null
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT06721949"
        },
        {
          "label": "RECLAIM current sites and contacts",
          "url": "https://www.reclaimtrial.ca/contact-us"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements.",
      "treatment_ids": [
        "taurine"
      ]
    },
    {
      "id": "NCT06156176",
      "title": "PREFACER rehabilitation trial",
      "summary": "Compares an eight-week rehabilitation programme with usual care for fatigue after COVID-19. Includes exercise sessions; ask about PEM screening and stopping rules.",
      "format": "Remote sessions and in-person assessments",
      "type": "Clinical trial",
      "status": "RECRUITING",
      "status_group": "verify",
      "source_updated": "2025-08-01",
      "checked": "2026-10-13",
      "start": {
        "date": "2025-04-01",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "Parkwood Hospital - St. Joseph's Health Care London",
          "city": "London",
          "province": "Ontario",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Ontario"
      ],
      "contact": [
        {
          "name": "Nicole Billias, BPH, CPT",
          "email": "Nicole.Billias@sjhc.london.on.ca",
          "phone": "519-646-6100 ext. 42558"
        },
        {
          "name": "Arden Lawson, BMSc",
          "email": "Arden.Lawson@sjhc.london.on.ca",
          "phone": "519-646-6100 ext. 42570"
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT06156176"
        },
        {
          "label": "PREFACER published protocol",
          "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC12598962/"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "The published protocol describes two 50-minute remote rehabilitation sessions weekly for eight weeks, follow-up over 24 weeks, and in-person assessments including brain-stimulation testing at Parkwood. Ask about PEM screening, stopping rules, travel and the current schedule.",
      "verification_note": "The registry still says recruiting, but was last updated 1 August 2025 and its estimated April 2026 completion has passed. The published protocol does not confirm current openings. Ask whether the separate Western fatigue poster is recruitment for this trial.",
      "verification_checked": "2026-10-13",
      "verification_method": "Public sources only; no study-team contact",
      "registry_last_known_status": null,
      "related_listing": "western-fatigue"
    },
    {
      "id": "NCT07374562",
      "title": "Stellate ganglion block — Trois-Rivières",
      "summary": "Randomized trial comparing a nerve block with a control injection, with symptom and functional assessments over 26 weeks.",
      "format": "In person",
      "type": "Clinical trial",
      "status": "RECRUITING",
      "status_group": "recruiting",
      "source_updated": "2026-02-09",
      "checked": "2026-10-14",
      "start": {
        "date": "2026-02-05",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "Centre hospitalier affilié universitaire régional",
          "city": "Trois-Rivières",
          "province": "Quebec",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Quebec"
      ],
      "contact": [
        {
          "name": "Marie-Claude Lehoux, Master's degree",
          "email": "marie-claude.lehoux@ssss.gouv.qc.ca",
          "phone": "819 697-3333 ext. 60753"
        },
        {
          "name": "Éva Mathieu, Ph.D",
          "email": "eva.mathieu@ssss.gouv.qc.ca",
          "phone": "819-697-3333 ext. 60756"
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT07374562"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements.",
      "treatment_ids": [
        "sgb"
      ]
    },
    {
      "id": "NCT07468604",
      "title": "Cervicothoracic sympathetic block — Toronto",
      "summary": "Investigates a sympathetic nerve block for post-COVID condition. Site-specific recruitment differs between the two Toronto listings.",
      "format": "In person",
      "type": "Clinical trial",
      "status": "RECRUITING",
      "status_group": "recruiting",
      "source_updated": "2026-10-09",
      "checked": "2026-10-14",
      "start": {
        "date": "2026-05-19",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "Women's College Hospital",
          "city": "Toronto",
          "province": "Ontario",
          "status": "NOT_YET_RECRUITING"
        },
        {
          "facility": "Toronto Western Hospital",
          "city": "Toronto",
          "province": "Ontario",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Ontario"
      ],
      "contact": [
        {
          "name": "Emad Al Azazi, MD, PhD",
          "email": "emad.al-azazi@uhn.ca",
          "phone": "4166035800"
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT07468604"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements.",
      "treatment_ids": [
        "sgb"
      ]
    },
    {
      "id": "NCT07312409",
      "title": "York University — taurine and circulation",
      "summary": "Examines vascular function and responses to upright posture before and after taurine supplementation. Registered as observational, although supplementation is involved.",
      "format": "In person",
      "type": "Observational study",
      "status": "RECRUITING",
      "status_group": "recruiting",
      "source_updated": "2026-06-05",
      "checked": "2026-10-13",
      "start": {
        "date": "2026-06-01",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": "65 Years",
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "York University",
          "city": "Toronto",
          "province": "Ontario",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Ontario"
      ],
      "contact": [
        {
          "name": "Heather Edgell, PhD",
          "email": "edgell@yorku.ca",
          "phone": "14167362100"
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT07312409"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements."
    },
    {
      "id": "NCT05019963",
      "title": "Technology-supported rehabilitation",
      "summary": "Evaluates rehabilitation supported by wearable technology for people receiving Long COVID care at The Ottawa Hospital. Current recruitment is unverified.",
      "format": "Confirm with team",
      "type": "Clinical trial",
      "status": "UNKNOWN",
      "status_group": "verify",
      "source_updated": "2024-07-03",
      "checked": "2026-10-13",
      "start": {
        "date": "2022-05-02",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "Ottawa Hospital Research Institute",
          "city": "Ottawa",
          "province": "Ontario",
          "status": "Not specified"
        }
      ],
      "provinces": [
        "Ontario"
      ],
      "contact": [],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT05019963"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements.",
      "verification_note": "The registry remains unknown (last updated 3 July 2024); its last known status was active, not recruiting. The lab study link returned a missing-page response. Neither establishes current enrolment.",
      "verification_checked": "2026-10-13",
      "verification_method": "Public sources only; no study-team contact",
      "registry_last_known_status": "ACTIVE_NOT_RECRUITING"
    },
    {
      "id": "NCT06907251",
      "title": "Dapagliflozin for Long COVID",
      "summary": "Planned randomized comparison of dapagliflozin with placebo over 12 months. Not yet recruiting; an estimated start date is not an invitation to enrol.",
      "format": "Confirm with team",
      "type": "Clinical trial",
      "status": "NOT_YET_RECRUITING",
      "status_group": "upcoming",
      "source_updated": "2026-07-01",
      "checked": "2026-10-15",
      "start": {
        "date": "2026-09-01",
        "type": "ESTIMATED"
      },
      "age_min": "18 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "University of Ottawa Heart Institute",
          "city": "Ottawa",
          "province": "Ontario",
          "status": "Not specified"
        }
      ],
      "provinces": [
        "Ontario"
      ],
      "contact": [
        {
          "name": "Poppy Dr. Ian Paterson",
          "email": "dpaterson@ottawaheart.ca",
          "phone": "1-613-696-7000"
        },
        {
          "name": "Poppy MacPhee",
          "email": "pmacphee@ottawaheart.ca",
          "phone": "613-696-7000 ext. 14646"
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT06907251"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements.",
      "treatment_ids": [
        "dapagliflozin"
      ]
    },
    {
      "id": "NCT05459506",
      "title": "Autoimmunity after COVID-19",
      "summary": "Observational research into immune changes and persistent symptoms. Overall registry status is unknown despite an old recruiting label on the Hamilton site.",
      "format": "In person",
      "type": "Observational study",
      "status": "UNKNOWN",
      "status_group": "verify",
      "source_updated": "2023-02-14",
      "checked": "2026-10-13",
      "start": {
        "date": "2021-06-25",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "St. Joseph's Healthcare Hamilton",
          "city": "Hamilton",
          "province": "Ontario",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Ontario"
      ],
      "contact": [
        {
          "name": "Snehal Somalwar",
          "email": "ssomalwa@stjoes.ca",
          "phone": "905-522-1155 ext. 35594"
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT05459506"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements.",
      "verification_note": "The registry remains unknown, with no update since 14 February 2023. The Hamilton site's old recruiting label does not confirm openings now. Contact details are registry-listed, not verified by a team reply.",
      "verification_checked": "2026-10-13",
      "verification_method": "Public sources only; no study-team contact",
      "registry_last_known_status": "RECRUITING"
    },
    {
      "id": "NCT05705648",
      "title": "Dietary oils and cognitive symptoms",
      "summary": "Compares supplemental oils and follows cognitive symptoms after COVID-19. Includes cognitive and imaging assessments; recruitment is closed.",
      "format": "In person",
      "type": "Clinical trial",
      "status": "ACTIVE_NOT_RECRUITING",
      "status_group": "ongoing",
      "source_updated": "2026-07-17",
      "checked": "2026-10-13",
      "start": {
        "date": "2023-10-01",
        "type": "ACTUAL"
      },
      "age_min": "22 Years",
      "age_max": "50 Years",
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "University of Alberta",
          "city": "Edmonton",
          "province": "Alberta",
          "status": "Not specified"
        }
      ],
      "provinces": [
        "Alberta"
      ],
      "contact": [],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT05705648"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements."
    },
    {
      "id": "NCT06086366",
      "title": "Brain imaging after COVID-related depression",
      "summary": "Observational brain-imaging study in people with a new major depressive episode after COVID-19. Specific medication and health exclusions apply.",
      "format": "In person",
      "type": "Observational study",
      "status": "RECRUITING",
      "status_group": "recruiting",
      "source_updated": "2026-02-11",
      "checked": "2026-10-13",
      "start": {
        "date": "2023-08-22",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": "75 Years",
      "healthy_volunteers": true,
      "locations": [
        {
          "facility": "Centre for Addiction and Mental Health",
          "city": "Toronto",
          "province": "Ontario",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Ontario"
      ],
      "contact": [
        {
          "name": "Karida Liu",
          "email": "liuyuhan0830@gmail.com",
          "phone": "416-535-8501"
        },
        {
          "name": "Jeffrey Meyer",
          "email": "jeffrey.meyer@utoronto.ca",
          "phone": "416-535-8501"
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT06086366"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements."
    },
    {
      "id": "NCT06928272",
      "title": "LC-REVITALIZE",
      "summary": "International study of repurposed medicines, including upadacitinib and pirfenidone. Montreal and Sherbrooke are listed as recruiting; confirm which treatment arms are available locally.",
      "format": "In person",
      "type": "Clinical trial",
      "status": "RECRUITING",
      "status_group": "recruiting",
      "source_updated": "2026-10-06",
      "checked": "2026-10-14",
      "start": {
        "date": "2025-09-10",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": "65 Years",
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "Institut de Recherches Cliniques de Montréal (IRCM)",
          "city": "Montreal",
          "province": "Quebec",
          "status": "RECRUITING"
        },
        {
          "facility": "Centre de Recherche du CHUS (CRCHUS)",
          "city": "Sherbrooke",
          "province": "Quebec",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Quebec"
      ],
      "contact": [
        {
          "name": "Stephanie Perkin",
          "email": "stephanie.perkin@lhsc.on.ca",
          "phone": "1-519-685-8500"
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT06928272"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements.",
      "treatment_ids": [
        "upadacitinib",
        "pirfenidone"
      ]
    },
    {
      "id": "NCT05914649",
      "title": "Calgary — brain fog, Long COVID and POTS",
      "summary": "Tests whether intravenous saline changes cognitive performance in Long COVID and POTS. Healthy comparison participants are also included.",
      "format": "In person",
      "type": "Clinical trial",
      "status": "RECRUITING",
      "status_group": "recruiting",
      "source_updated": "2026-05-07",
      "checked": "2026-10-13",
      "start": {
        "date": "2024-09-19",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": "60 Years",
      "healthy_volunteers": true,
      "locations": [
        {
          "facility": "University of Calgary",
          "city": "Calgary",
          "province": "Alberta",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Alberta"
      ],
      "contact": [
        {
          "name": "Satish R Raj, MD MSCI",
          "email": "autonomic.research@ucalgary.ca",
          "phone": "(403)210-6152"
        },
        {
          "name": "Rasha Hamzeh, RN",
          "email": "autonomic.research@ucalgary.ca",
          "phone": null
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT05914649"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements."
    },
    {
      "id": "NCT07454395",
      "title": "Swimming tolerance in ME/CFS and related conditions",
      "summary": "Remote pilot examining responses to self-paced swimming in selected people with mild-to-moderate illness. The registry currently says suspended.",
      "format": "Remote",
      "type": "Clinical trial",
      "status": "SUSPENDED",
      "status_group": "paused",
      "source_updated": "2026-03-30",
      "checked": "2026-10-13",
      "start": {
        "date": "2026-02-20",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": "80 Years",
      "healthy_volunteers": true,
      "locations": [
        {
          "facility": "Simon Fraser University",
          "city": "Burnaby",
          "province": "British Columbia",
          "status": "Not specified"
        }
      ],
      "provinces": [
        "British Columbia"
      ],
      "contact": [],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT07454395"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements."
    },
    {
      "id": "NCT04736732",
      "title": "IRCM post-COVID research clinic and biobank",
      "summary": "Follows recovery and organ-related outcomes after infection, with several comparison groups and a biobank. Quebec residency and other criteria apply.",
      "format": "In person",
      "type": "Observational study",
      "status": "RECRUITING",
      "status_group": "recruiting",
      "source_updated": "2026-04-17",
      "checked": "2026-10-13",
      "start": {
        "date": "2021-02-01",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": "100 Years",
      "healthy_volunteers": true,
      "locations": [
        {
          "facility": "Institut de Recherches Cliniques de Montreal",
          "city": "Montreal",
          "province": "Quebec",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Quebec"
      ],
      "contact": [
        {
          "name": "Emilia Liana Falcone, M.D., Ph.D.",
          "email": "Emilia.falcone@ircm.qc.ca",
          "phone": "514-987-5610"
        },
        {
          "name": "Charlotte Du Sablon, M.Sc.",
          "email": "Charlotte.Dusablon@ircm.qc.ca",
          "phone": "514-987-5581"
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT04736732"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements."
    },
    {
      "id": "NCT06055270",
      "title": "Nerve block for post-COVID smell distortion",
      "summary": "Trial of a stellate ganglion block for persistent parosmia. Registry status is unknown; an old London site listing is not current recruitment confirmation.",
      "format": "In person",
      "type": "Clinical trial",
      "status": "UNKNOWN",
      "status_group": "verify",
      "source_updated": "2024-10-23",
      "checked": "2026-10-13",
      "start": {
        "date": "2024-02-15",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": "70 Years",
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "St. Joseph's Hospital London",
          "city": "London",
          "province": "Ontario",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Ontario"
      ],
      "contact": [
        {
          "name": "Lanette Friesen-Waldner, Ph.D",
          "email": "lanette.friesen-waldner@sjhc.london.on.ca",
          "phone": "5196466100 ext. 61125"
        },
        {
          "name": "Cristian Dihel, MD",
          "email": "cristian.dihel@sjhc.london.on.ca",
          "phone": null
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT06055270"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements.",
      "verification_note": "The registry remains unknown, with no update since 23 October 2024. Its estimated May 2026 completion has passed. The London site's old recruiting label does not confirm current openings.",
      "verification_checked": "2026-10-13",
      "verification_method": "Public sources only; no study-team contact",
      "registry_last_known_status": "RECRUITING"
    },
    {
      "id": "NCT06928506",
      "title": "RECLAIM — Hi-OxSR breathing device",
      "summary": "Investigates a breathing device for persistent cognitive symptoms. RECLAIM lists enrolment as open; confirm your local site's availability because the website and older registry differ.",
      "format": "In person",
      "type": "Clinical trial",
      "status": "RECRUITING",
      "status_group": "recruiting",
      "source_updated": "2025-09-15",
      "checked": "2026-10-14",
      "start": {
        "date": "2025-08-01",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "Kaye Edmonton Clinic",
          "city": "Edmonton",
          "province": "Alberta",
          "status": "NOT_YET_RECRUITING"
        },
        {
          "facility": "University Health Network",
          "city": "Toronto",
          "province": "Ontario",
          "status": "RECRUITING"
        },
        {
          "facility": "Centre Hospitalier Universitaire de Sherbrooke",
          "city": "Sherbrooke",
          "province": "Quebec",
          "status": "NOT_YET_RECRUITING"
        }
      ],
      "provinces": [
        "Alberta",
        "Ontario",
        "Quebec"
      ],
      "contact": [
        {
          "name": "Suzanne Cohen",
          "email": "reclaim@uhn.ca",
          "phone": "1-866-673-2524"
        },
        {
          "name": "Christine Rioux-Perreault — Sherbrooke",
          "email": "christine.rioux-perreault.ciussse-chus@ssss.gouv.qc.ca",
          "phone": null
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT06928506"
        },
        {
          "label": "RECLAIM current sites and contacts",
          "url": "https://www.reclaimtrial.ca/contact-us"
        },
        {
          "label": "RECLAIM current interventions and enrolment",
          "url": "https://www.reclaimtrial.ca/current-interventions"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements.",
      "verification_note": "RECLAIM's current-interventions page explicitly lists enrolment as open, and its contact page lists Toronto, Sherbrooke and Edmonton for Hi-OxSR. The older registry still marks Sherbrooke and Edmonton as not yet recruiting. Confirm local availability with the team; the website does not state an update date.",
      "verification_checked": "2026-10-13",
      "verification_method": "Public sources only; no study-team contact",
      "registry_last_known_status": null,
      "recruitment_basis": {
        "type": "study_team_website",
        "checked": "2026-10-13",
        "url": "https://www.reclaimtrial.ca/current-interventions",
        "source_updated": null
      },
      "treatment_ids": [
        "hioxsr"
      ]
    },
    {
      "id": "NCT05268523",
      "title": "Education and mindfulness for self-management",
      "summary": "Compares group programmes for managing Long COVID symptoms. The recruiting record is old and its estimated completion has passed.",
      "format": "Remote",
      "type": "Clinical trial",
      "status": "RECRUITING",
      "status_group": "verify",
      "source_updated": "2024-11-25",
      "checked": "2026-10-13",
      "start": {
        "date": "2021-11-23",
        "type": "ACTUAL"
      },
      "age_min": "18 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "Toronto Rehabilitation Institute",
          "city": "Toronto",
          "province": "Ontario",
          "status": "RECRUITING"
        }
      ],
      "provinces": [
        "Ontario"
      ],
      "contact": [
        {
          "name": "Julia Rybkina, MSc",
          "email": "julia.rybkina@uhn.ca",
          "phone": "416-597-3422 ext. 7651"
        },
        {
          "name": "Nithin Jacob, MSc",
          "email": "helpscovid@uhn.ca",
          "phone": "416-597-3422"
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT05268523"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements.",
      "verification_note": "The registry still says recruiting, but was last updated 25 November 2024 and its estimated December 2025 completion has passed. No newer study-team confirmation of openings was found.",
      "verification_checked": "2026-10-13",
      "verification_method": "Public sources only; no study-team contact",
      "registry_last_known_status": null
    },
    {
      "id": "NCT05125510",
      "title": "CANCOV Canadian follow-up cohort",
      "summary": "Tracks recovery and longer-term outcomes in people who had COVID-19 and family caregivers. Ongoing follow-up; not accepting new participants.",
      "format": "Confirm with team",
      "type": "Observational study",
      "status": "ACTIVE_NOT_RECRUITING",
      "status_group": "ongoing",
      "source_updated": "2025-08-14",
      "checked": "2026-10-13",
      "start": {
        "date": "2020-06-17",
        "type": "ACTUAL"
      },
      "age_min": "16 Years",
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "Alberta Health Services",
          "city": "Calgary",
          "province": "Alberta",
          "status": "Not specified"
        },
        {
          "facility": "Providence Healthcare",
          "city": "Vancouver",
          "province": "British Columbia",
          "status": "Not specified"
        },
        {
          "facility": "Health Sciences Centre and St. Boniface Hospital and Grace Hospital",
          "city": "Winnipeg",
          "province": "Manitoba",
          "status": "Not specified"
        },
        {
          "facility": "William Osler Health System",
          "city": "Etobicoke",
          "province": "Ontario",
          "status": "Not specified"
        },
        {
          "facility": "St Joseph's Health Centre",
          "city": "Hamilton",
          "province": "Ontario",
          "status": "Not specified"
        },
        {
          "facility": "The Ottawa Hospital",
          "city": "Ottawa",
          "province": "Ontario",
          "status": "Not specified"
        },
        {
          "facility": "Unity Health (St Michaels Health Centre_",
          "city": "Toronto",
          "province": "Ontario",
          "status": "Not specified"
        },
        {
          "facility": "Mount Sinai Hospital",
          "city": "Toronto",
          "province": "Ontario",
          "status": "Not specified"
        },
        {
          "facility": "University Health Network, Osteoporosis Department",
          "city": "Toronto",
          "province": "Ontario",
          "status": "Not specified"
        },
        {
          "facility": "Hospital for Sick Children",
          "city": "Toronto",
          "province": "Ontario",
          "status": "Not specified"
        },
        {
          "facility": "Michael Garron Hospital",
          "city": "Toronto",
          "province": "Ontario",
          "status": "Not specified"
        },
        {
          "facility": "McGill University Health Centre",
          "city": "Montreal",
          "province": "Quebec",
          "status": "Not specified"
        },
        {
          "facility": "Montreal Jewish General",
          "city": "Montreal",
          "province": "Quebec",
          "status": "Not specified"
        },
        {
          "facility": "University of Sherbrooke",
          "city": "Sherbrooke",
          "province": "Quebec",
          "status": "Not specified"
        }
      ],
      "provinces": [
        "Alberta",
        "British Columbia",
        "Manitoba",
        "Ontario",
        "Quebec"
      ],
      "contact": [],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT05125510"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements."
    },
    {
      "id": "NCT07697261",
      "title": "FALCON — Lightning Process and activity pacing",
      "summary": "Planned online randomized comparison for Long COVID. McMaster-led; no Canadian site list is published. Confirm geographic eligibility with the team. LCAC has a separate campaign concerning this trial.",
      "format": "Remote",
      "type": "Clinical trial",
      "status": "NOT_YET_RECRUITING",
      "status_group": "upcoming",
      "source_updated": "2026-07-13",
      "checked": "2026-10-13",
      "start": {
        "date": "2026-11",
        "type": "ESTIMATED"
      },
      "age_min": "18 Years",
      "age_max": "65 Years",
      "healthy_volunteers": false,
      "locations": [],
      "provinces": [
        "Ontario"
      ],
      "contact": [
        {
          "name": "Dr. Jason Busse, PhD, Professor",
          "email": "bussejw@mcmaster.ca",
          "phone": "(905) 525-9140"
        },
        {
          "name": "Rozina Thobani, MSc",
          "email": "thobar1@mcmaster.ca",
          "phone": null
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT07697261"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Online delivery is planned; geographic eligibility and PEM accommodations need confirmation."
    },
    {
      "id": "NCT04949386",
      "title": "S-1226 for persistent respiratory symptoms",
      "summary": "Older planned trial for respiratory symptoms after COVID-19. No current site list or recruitment confirmation was found; retained for transparency.",
      "format": "Confirm with team",
      "type": "Clinical trial",
      "status": "UNKNOWN",
      "status_group": "verify",
      "source_updated": "2021-08-23",
      "checked": "2026-10-13",
      "start": {
        "date": "2021-09",
        "type": "ESTIMATED"
      },
      "age_min": "18 Years",
      "age_max": "80 Years",
      "healthy_volunteers": false,
      "locations": [],
      "provinces": [
        "Alberta"
      ],
      "contact": [
        {
          "name": "John Dennis, PhD",
          "email": "jdennis@solaeromed.com",
          "phone": "403-689-5989"
        },
        {
          "name": "Francis Green, MBChB, MD",
          "email": "fgreen@ucalgary.ca",
          "phone": "403-220-4514"
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT04949386"
        }
      ],
      "eligibility_note": "Age is only one criterion. Read the full inclusion and exclusion criteria and ask the study team to assess eligibility.",
      "participation_note": "Ask the study team about visits, time, travel, compensation, accessibility and any exertion or testing requirements.",
      "verification_note": "The registry remains unknown, with no update since 23 August 2021. Its last known status was not yet recruiting and no sites are listed. The old planned dates do not establish an upcoming opportunity.",
      "verification_checked": "2026-10-13",
      "verification_method": "Public sources only; no study-team contact",
      "registry_last_known_status": "NOT_YET_RECRUITING"
    },
    {
      "id": "sfu-emergency-care",
      "title": "Long COVID experiences in emergency care",
      "summary": "Simon Fraser University is seeking accounts of care in British Columbia emergency departments and urgent care centres to help develop educational resources.",
      "provinces": [
        "British Columbia"
      ],
      "format": "Confirm with team",
      "type": "Interviews / surveys",
      "status_group": "recruiting",
      "status": "TEAM_PAGE_LISTS_RECRUITING",
      "source_updated": null,
      "checked": "2026-10-13",
      "locations": [],
      "contact": [
        {
          "name": "Study team",
          "email": "sfu-longcovid@sfu.ca"
        }
      ],
      "sources": [
        {
          "label": "Institutional / study-team page",
          "url": "https://ohhiscience.ca/long-covid"
        }
      ],
      "eligibility_note": "People with Long COVID who have used BC emergency or urgent care. Ask the team about other criteria.",
      "participation_note": "Format, time commitment and compensation: confirm with team."
    },
    {
      "id": "gait-balance",
      "title": "Long COVID, walking and balance",
      "summary": "The RELEARN laboratory is recruiting people with Long COVID for gait and balance research. Contact the team for the current assessment schedule.",
      "provinces": [
        "Ontario"
      ],
      "format": "In person",
      "type": "Observational study",
      "status_group": "recruiting",
      "status": "TEAM_PAGE_LISTS_RECRUITING",
      "source_updated": null,
      "checked": "2026-10-13",
      "locations": [],
      "contact": [
        {
          "name": "Study team",
          "email": "janna.marvyn@uhn.ca"
        }
      ],
      "sources": [
        {
          "label": "Institutional / study-team page",
          "url": "https://relearnlab.wordpress.com/current-research/"
        }
      ],
      "eligibility_note": "People with Long COVID; detailed age and exclusion criteria need confirmation.",
      "participation_note": "Ask about walking tasks, exertion, travel and PEM accommodations."
    },
    {
      "id": "prairie-self-care",
      "title": "Fatigue, self-care and mental health",
      "summary": "University of Saskatchewan interviews and a survey explore fatigue and self-care after COVID-19.",
      "provinces": [
        "Alberta",
        "Saskatchewan",
        "Manitoba"
      ],
      "format": "Remote",
      "type": "Interviews / surveys",
      "status_group": "verify",
      "status": "NETWORK_LISTING_REQUIRES_CONFIRMATION",
      "source_updated": null,
      "checked": "2026-10-13",
      "locations": [],
      "contact": [
        {
          "name": "Study team",
          "email": "donna.goodridge@usask.ca"
        }
      ],
      "sources": [
        {
          "label": "Research-team recruitment poster",
          "url": "https://www.longcovidweb.ca/_files/ugd/a3d7a1_3a365ec755e447d69dc0309e7739999f.pdf"
        },
        {
          "label": "Long COVID Web listing",
          "url": "https://www.longcovidweb.ca/research/recruitment-for-current-studies"
        }
      ],
      "eligibility_note": "Ages 30–55 in the Prairie provinces, with post-COVID fatigue and mental health challenges; internet and family-doctor access required.",
      "participation_note": "A 30–45 minute survey and two 45–60 minute video interviews; poster offers $50. Confirm availability.",
      "verification_note": "The research-team poster and Long COVID Web listing remain available, but do not give a current recruitment confirmation date. Ask the listed investigator whether places remain.",
      "verification_checked": "2026-10-13",
      "verification_method": "Public sources only; no study-team contact"
    },
    {
      "id": "family-care",
      "title": "Person and family-centred Long COVID care",
      "summary": "University of Toronto researchers interview people with Long COVID, caregivers and healthcare professionals about how care should be organized.",
      "provinces": [
        "Across Canada"
      ],
      "format": "Remote",
      "type": "Interviews / surveys",
      "status_group": "verify",
      "status": "NETWORK_LISTING_REQUIRES_CONFIRMATION",
      "source_updated": null,
      "checked": "2026-10-13",
      "locations": [],
      "contact": [
        {
          "name": "Study team",
          "email": "Caregiving.Study@utoronto.ca",
          "phone": "416-978-5694"
        }
      ],
      "sources": [
        {
          "label": "Research-team recruitment poster",
          "url": "https://www.longcovidweb.ca/_files/ugd/a3d7a1_d640561e4d494e65a9c9c36ad18b3ebf.pdf"
        },
        {
          "label": "Long COVID Web listing",
          "url": "https://www.longcovidweb.ca/research/recruitment-for-current-studies"
        },
        {
          "label": "University of Toronto 2026 research presentations",
          "url": "https://rehabcovidnetwork.med.utoronto.ca/poster-presentations-2026-international-forum-covid-rehabilitation-research"
        }
      ],
      "eligibility_note": "Canadian adults with Long COVID, eligible caregivers or healthcare professionals; English communication required.",
      "participation_note": "One approximately one-hour telephone or video interview. Poster dated September 2024; current recruitment needs confirmation.",
      "verification_note": "The recruitment poster remains available and the team presented related work in April 2026. Neither confirms that interviews are still open. Ask the team about current recruitment.",
      "verification_checked": "2026-10-13",
      "verification_method": "Public sources only; no study-team contact"
    },
    {
      "id": "ubc-biomarkers",
      "title": "Patient perspectives on diagnostic biomarkers",
      "summary": "UBC researchers seek patient and clinician perspectives to inform blood-based diagnostic research. This listing is for an interview, not access to a validated diagnostic test.",
      "provinces": [
        "British Columbia"
      ],
      "format": "Remote or in person",
      "type": "Interviews / surveys",
      "status_group": "verify",
      "status": "NETWORK_LISTING_REQUIRES_CONFIRMATION",
      "source_updated": null,
      "checked": "2026-10-13",
      "locations": [],
      "contact": [
        {
          "name": "Study team",
          "email": "estefania.espin@hli.ubc.ca"
        }
      ],
      "sources": [
        {
          "label": "Research-team recruitment poster",
          "url": "https://www.longcovidweb.ca/_files/ugd/a3d7a1_2803c467c6af4cc6a5224963d5eda2f5.pdf"
        },
        {
          "label": "Long COVID Web listing",
          "url": "https://www.longcovidweb.ca/research/recruitment-for-current-studies"
        },
        {
          "label": "Researcher's August 2026 project update",
          "url": "https://www.hli.ubc.ca/2026/08/how-long-covid-affects-the-immune-system-and-metabolism-in-non-hospitalized-healthcare-workers/"
        }
      ],
      "eligibility_note": "Adults with diagnosed or suspected Long COVID, or clinicians with diagnostic experience. Geographic eligibility needs confirmation.",
      "participation_note": "A screening questionnaire and roughly 30-minute interview by Zoom or in person; compensation offered, amount unspecified.",
      "verification_note": "An August 2026 researcher update says a patient/clinician qualitative study was under review. The older interview poster does not establish that this recruitment is still open; ask whether it has ended or moved to another phase.",
      "verification_checked": "2026-10-13",
      "verification_method": "Public sources only; no study-team contact"
    },
    {
      "id": "western-fatigue",
      "title": "Following Long COVID fatigue over time",
      "summary": "Western University researchers follow fatigue and usual-care costs over 24 weeks.",
      "provinces": [
        "Ontario"
      ],
      "format": "Remote",
      "type": "Observational study",
      "status_group": "verify",
      "status": "NETWORK_LISTING_REQUIRES_CONFIRMATION",
      "source_updated": null,
      "checked": "2026-10-13",
      "locations": [],
      "contact": [
        {
          "name": "Study team",
          "email": "Nicole.Billias@sjhc.london.on.ca"
        }
      ],
      "sources": [
        {
          "label": "Research-team recruitment poster",
          "url": "https://www.longcovidweb.ca/_files/ugd/a3d7a1_b0f0eba8d0464b028c57d825cb220bfe.pdf"
        },
        {
          "label": "Long COVID Web listing",
          "url": "https://www.longcovidweb.ca/research/recruitment-for-current-studies"
        },
        {
          "label": "PREFACER protocol — possible related listing",
          "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC12598962/"
        }
      ],
      "eligibility_note": "Adults with fatigue after COVID-19 who speak English and can use internet-based video calls. Geographic eligibility needs confirmation.",
      "participation_note": "Poster dated March 2025. Confirm the current schedule, recruitment and compensation.",
      "verification_note": "The March 2025 poster remains listed. Its team, 24-week duration and description overlap with the observational recruitment approach in the PREFACER protocol. This may be a linked listing, not a separate study; ask the team to confirm.",
      "verification_checked": "2026-10-13",
      "verification_method": "Public sources only; no study-team contact",
      "related_listing": "NCT06156176"
    },
    {
      "id": "communit",
      "title": "CommUNIT: underrepresented communities",
      "summary": "McMaster-led research examines post-COVID condition and diagnostic challenges among racialized, multi-ethnic and recently immigrated communities.",
      "provinces": [
        "Ontario"
      ],
      "format": "Confirm with team",
      "type": "Observational study",
      "status_group": "verify",
      "status": "NETWORK_LISTING_REQUIRES_CONFIRMATION",
      "source_updated": null,
      "checked": "2026-10-13",
      "locations": [],
      "contact": [
        {
          "name": "Study team",
          "email": "covid.community.on@phri.ca",
          "phone": "289-775-1356"
        }
      ],
      "sources": [
        {
          "label": "Research-team recruitment poster",
          "url": "https://www.longcovidweb.ca/_files/ugd/a3d7a1_9b85348117d94beda8c1cdacb16cebed.pdf"
        },
        {
          "label": "Long COVID Web listing",
          "url": "https://www.longcovidweb.ca/research/recruitment-for-current-studies"
        }
      ],
      "eligibility_note": "Greater Toronto/Hamilton residents from the named communities, aged 18 or older at a positive COVID infection.",
      "participation_note": "Compensation offered; schedule and format unspecified. December 2024 poster needs current recruitment confirmation.",
      "verification_note": "The December 2024 poster remains listed, but no newer study-team recruitment confirmation was found. The linked project website could not be retrieved during this check. Use the poster's phone or email to ask about availability.",
      "verification_checked": "2026-10-13",
      "verification_method": "Public sources only; no study-team contact"
    },
    {
      "id": "calgary-breathlessness",
      "title": "Investigating persistent breathlessness",
      "summary": "University of Calgary research investigates the causes of breathlessness after COVID-19 using lung and cardiovascular assessments.",
      "provinces": [
        "Alberta"
      ],
      "format": "In person",
      "type": "Observational study",
      "status_group": "recruiting",
      "status": "TEAM_PAGE_LISTS_RECRUITING",
      "source_updated": null,
      "checked": "2026-10-13",
      "locations": [],
      "contact": [],
      "sources": [
        {
          "label": "Institutional / study-team page",
          "url": "https://research.ucalgary.ca/participate/evaluation-pulmonary-vascular-disease-patients-long-covid-and-dyspnea-reb21-1381"
        }
      ],
      "eligibility_note": "Adults with persistent breathlessness more than 12 weeks after COVID-19; recovered volunteers and people with pulmonary hypertension may also qualify.",
      "participation_note": "Includes chest X-ray, lung-function tests, CPET and right-heart catheterization with exercise. Ask about risks and PEM safeguards; contact 403-210-7861."
    },
    {
      "id": "NCT07682402",
      "title": "TaurineLCPeds — adolescent taurine study",
      "summary": "University of Alberta-led, open-label study for ages 10–17. Health Canada and research ethics approvals are pending. There is no firm recruitment date; study sites remain unconfirmed.",
      "format": "Confirm with team",
      "type": "Clinical trial",
      "status": "NOT_YET_RECRUITING",
      "status_group": "upcoming",
      "source_updated": "2026-08-13",
      "checked": "2026-10-15",
      "start": {
        "date": "2026-09-30",
        "type": "ESTIMATED"
      },
      "age_min": "10 Years",
      "age_max": "17 Years",
      "healthy_volunteers": false,
      "locations": [],
      "provinces": [
        "Alberta"
      ],
      "coverage_note": "Alberta identifies the study sponsor; participant locations and travel requirements are unconfirmed.",
      "contact": [
        {
          "name": "Lawrence Richer, MD, MSc",
          "email": "lricher@ualberta.ca",
          "phone": "780-492-0943"
        },
        {
          "name": "Ellen Morrison, PhD",
          "email": "taurineLC@ualberta.ca",
          "phone": null
        }
      ],
      "sources": [
        {
          "label": "ClinicalTrials.gov record and eligibility",
          "url": "https://clinicaltrials.gov/study/NCT07682402"
        }
      ],
      "eligibility_note": "Age is only one criterion. The study requires participant assent and parent/guardian consent; the team must assess eligibility.",
      "participation_note": "Three months of supplementation with blood sampling and symptom/cognitive assessments. Ask about study locations, visit schedule, accessibility, travel and current opening date. The primary outcome is change in blood taurine, not proof of symptom benefit.",
      "treatment_ids": [
        "taurine"
      ],
      "team_confirmation": {
        "date": "2026-10-15",
        "source": "Email from Ellen, TaurineLC study team, to LCAC",
        "summary": "Health Canada and research ethics approvals are pending, with no firm approval or recruitment timeline. The team offered further information and a recruitment flyer once approvals are received."
      }
    },
    {
      "id": "patient-experience-project",
      "title": "Long COVID Patient Experience Project",
      "summary": "Canadian online survey about Long COVID symptoms and their effects on daily life. Participants can choose which questions to answer and return to share changes over time. This is observational research, not a treatment trial.",
      "format": "Remote / online",
      "type": "Interviews / surveys",
      "status": "RECRUITING",
      "status_group": "recruiting",
      "source_updated": null,
      "checked": "2026-10-15",
      "age_min": null,
      "age_max": null,
      "healthy_volunteers": false,
      "locations": [
        {
          "facility": "University of British Columbia / Citizen Science research team",
          "city": "Vancouver",
          "province": "British Columbia",
          "status": "Online participation invited on the project website"
        }
      ],
      "provinces": [
        "British Columbia"
      ],
      "contact": [
        {
          "name": "Citizen Science research team",
          "email": "CitizenScience@arthritisresearch.ca",
          "phone": "1-844-707-4053"
        }
      ],
      "sources": [
        {
          "label": "Official Long COVID survey and participation page",
          "url": "https://patientscientist.ca/long-covid-survey"
        },
        {
          "label": "Participant FAQ, privacy and withdrawal information",
          "url": "https://patientscientist.ca/long-covid-survey/faq"
        }
      ],
      "eligibility_note": "The project invites people living in Canada with Long COVID symptoms. Confirm age requirements and full eligibility with the team; the reviewed public pages do not specify a minimum age. British Columbia identifies the research team, not a residency restriction.",
      "participation_note": "Online questions can be completed selectively, with breaks and return visits. Account registration uses an email address. Review the study consent and privacy information before sharing health details; the FAQ also describes personal health number data. Compensation and the time required were not established in this check.",
      "recruitment_basis": {
        "type": "study_team_website",
        "url": "https://patientscientist.ca/long-covid-survey",
        "checked": "2026-10-15"
      }
    },
    {
      "id": "york-language-processing",
      "title": "University of York — language processing",
      "summary": "Online questions and language tasks explore how Long COVID affects language processing. Run by the University of York in the UK.",
      "format": "Remote / online",
      "type": "Observational study",
      "status": "TEAM_PAGE_LISTS_RECRUITING",
      "status_group": "recruiting",
      "source_updated": null,
      "checked": "2026-10-16",
      "age_min": "18 Years",
      "age_max": null,
      "healthy_volunteers": true,
      "locations": [],
      "provinces": [
        "Across Canada"
      ],
      "contact": [
        {
          "name": "Dr Heidi Baseler, study supervisor",
          "email": "heidi.baseler@york.ac.uk"
        },
        {
          "name": "Study contact listed by Long COVID Web",
          "email": "NNK519@YORK.AC.UK"
        }
      ],
      "sources": [
        {
          "label": "Study information and consent",
          "url": "https://york.qualtrics.com/jfe/form/SV_aYngvQldJlbrvWC?Q_CHL=qr"
        },
        {
          "label": "Long COVID Web recruitment listing",
          "url": "https://www.longcovidweb.ca/research/recruitment-for-current-studies"
        }
      ],
      "eligibility_note": "Adults 18+, with or without Long COVID. The study asks whether English is your native language; the recruitment listing seeks native English speakers. No residency restriction is stated in the participant information. Listed here through Long COVID Web; confirm Canadian eligibility with the team. Across Canada describes online coverage, not a confirmed residency criterion.",
      "participation_note": "About 15 minutes, including health questions, word recognition and a two-minute timed comprehension task. Unpaid; no individual scores or diagnostic assessment. You can stop before completion by closing the page. The information sheet says responses are anonymous and cannot be removed after completion; anonymised data may be reused and shared internationally.",
      "recruitment_basis": {
        "type": "study_team_website",
        "url": "https://york.qualtrics.com/jfe/form/SV_aYngvQldJlbrvWC?Q_CHL=qr",
        "checked": "2026-10-16"
      }
    },
    {
      "id": "long-haul-campus-western",
      "title": "Long-Haul Campus Study — Western University",
      "summary": "Research comparing quality of life among Ontario university students with and without Long COVID, exploring lived experiences and support for academic success.",
      "format": "Remote / online questionnaire",
      "type": "Interviews / surveys",
      "status": "UNKNOWN",
      "status_group": "verify",
      "source_updated": null,
      "checked": "2026-10-16",
      "age_min": null,
      "age_max": null,
      "healthy_volunteers": true,
      "locations": [
        "Ontario university students"
      ],
      "provinces": [
        "Ontario"
      ],
      "contact": [
        {
          "name": "Varsha Vasudevan, study lead",
          "email": "vvasude@uwo.ca"
        },
        {
          "name": "Dr Jennifer Irwin, principal investigator",
          "email": "jenirwin@uwo.ca"
        }
      ],
      "sources": [
        {
          "label": "Study questionnaire and participation information (link supplied from flyer QR code)",
          "url": "https://uwo.eu.qualtrics.com/jfe/form/SV_dm7nGtfTcubGTjg?Q_CHL=qr"
        }
      ],
      "eligibility_note": "Full- or part-time students enrolled at an Ontario university (undergraduate, graduate or professional degree), able to read and write English and access an internet-connected device. Includes students with and without Long COVID.",
      "participation_note": "Questionnaire taking 10 minutes or less. Participants may be compensated; payment and amount are not guaranteed in the supplied flyer.",
      "verification_note": "Information supplied in a Western University recruitment flyer. The study questionnaire URL was supplied from the flyer QR code; current recruitment and deadline have not been independently confirmed.",
      "recruitment_basis": {
        "type": "supplied_recruitment_flyer",
        "url": "https://uwo.eu.qualtrics.com/jfe/form/SV_dm7nGtfTcubGTjg?Q_CHL=qr",
        "checked": "2026-10-16"
      }
    }
  ],
  "update_note": "Selected treatment-linked records checked 14 October 2026; other listings retain their individual check dates. Added TaurineLCPeds; no study team was contacted. Added the UK-led online York language study on 16 October 2026 after reviewing its participant information; Canadian eligibility is not explicitly confirmed. Existing recruitment labels retained."
}
